Concepedia

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

Carol-Anne Martin, Ilyas Ahmad, Anna Klingseisen, Muhammad Sajid Hussain, Louise S. Bicknell, Andrea Leitch, Gudrun Nürnberg, Mohammad R. Toliat, Jennie Murray, David Hunt,

Nature Genetics · 2014 · 183 citations · 45 references

DOI

Concepts

References

45

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

, , +17

Fast and accurate short read alignment with Burrows–Wheeler transform

Heng Li, Richard Durbin · Bioinformatics · 2009 · 62.8K citations · Full text

, , +12

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna, Matthew G. Hanna, Eric Banks et al. · Genome Research · 2010 · 30K citations · Full text

, , +17

Stages of embryonic development of the zebrafish

Charles B. Kimmel, William W. Ballard, Seth R. Kimmel et al. · Developmental Dynamics · 1995 · 12.3K citations

, , +17