Brendan P. Flynn

Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)

Brendan P. Flynn, Amit P. Bhole, Nima Saeidi et al. · PLoS ONE · 2010 · 193 citations · Full text

Mechanical strain enhances survivability of collagen micronetworks in the presence of collagenase: implications for load-bearing matrix growth and stability

Amit P. Bhole, Brendan P. Flynn, Melody Liles et al. · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · 2009 · 141 citations · Full text

Tissue Engineering, Collagen Fibrils, Engineering +23

Molecular Mechanochemistry: Low Force Switch Slows Enzymatic Cleavage of Human Type I Collagen Monomer

Robert James Camp, Melody Liles, John W. Beale et al. · Journal of the American Chemical Society · 2011 · 92 citations · Full text

Tissue Engineering, Engineering, Biomimetic Materials +25

Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown

Shu‐Wei Chang, Brendan P. Flynn, Jeffrey W. Ruberti et al. · Biomaterials · 2012 · 75 citations · Full text

Mechanobiology, Tissue Engineering, Engineering +12

Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure

Sason Torosean, Brendan P. Flynn, Johan Axelsson et al. · Nanomedicine Nanotechnology Biology and Medicine · 2012 · 68 citations · Full text

Nanoparticles, Nanomedicine, Engineering +11