Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence

Hiromichi Hara, Jun Araya, Saburo Ito, +14

American Journal of Physiology-Lung Cellular and Molecular Physiology

Cell DeathMitochondrial BiologyOxidative StressDynamic OrganellesTobacco Control +16

Autophagy Induction by SIRT6 through Attenuation of Insulin-like Growth Factor Signaling Is Involved in the Regulation of Human Bronchial Epithelial Cell Senescence

Naoki Takasaka, Jun Araya, Hiromichi Hara, +21

The Journal of Immunology

MitophagyInflammatory Lung DiseaseLung InflammationAutophagy ActivationImmunology +18

Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy

Yusuke Kurita, Jun Araya, Shunsuke Minagawa, +24

Respiratory Research

Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4

Kazuya Tsubouchi, Jun Araya, Shunsuke Minagawa, +25

Autophagy

Inflammatory Lung DiseaseLung InflammationPathologyPulmonary Alveolar ProteinosisLung Fibrosis Development +15

Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance

Masaru Usui, Yutaka Yoshii, Stanislas Thiriet-Rupert, +2

Communications Biology

Pathogens in COPD exacerbations identified by comprehensive real-time PCR plus older methods

Kenichiro Shimizu, Yutaka Yoshii, Miyuki Morozumi, +20

International Journal of COPD

Ehlers-Danlos Syndrome with Recurrent Spontaneous Pneumothoraces and Cavitary Lesion on Chest X-ray as the Initial Complications

Takashi Ishiguro, Noboru Takayanagi, Yoshinori Kawabata, +16

Internal Medicine

Ehlers-danlos SyndromeLeft Ulnar ArteryPneumothoraxPathologyPoint Mutation +9

Increased levels of prostaglandin E−major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia

Tsugumi Horikiri, Hiromichi Hara, Nayuta Saito, +20

Respiratory Medicine

InflammationFibrosisInflammatory Lung DiseaseLung InflammationMedicine +5

Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics

Yutaka Yoshii, Ken-ichi Okuda, Satomi Yamada, +8

npj Biofilms and Microbiomes

Effectiveness of hepatoprotective drugs for anti-tuberculosis drug-induced hepatotoxicity: a retrospective analysis

Zenya Saito, Yugo Kaneko, Akira Kinoshita, +8

BMC Infectious Diseases