Insufficient autophagy in idiopathic pulmonary fibrosis

Jun Araya, Jun Kojima, Naoki Takasaka, +16

American Journal of Physiology-Lung Cellular and Molecular Physiology

MitophagyInflammatory Lung DiseaseAdvanced Lung DiseaseLung InflammationImmunology +15

PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis

Saburo Ito, Jun Araya, Yusuke Kurita, +18

Autophagy

Copd PathogenesisMitophagyGeneticsApoptosisCell Death +16

Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

Satoko Fujii, Hiromichi Hara, Jun Araya, +14

OncoImmunology

MitophagyUbiquitinated ProteinsLung InflammationImmunologyOxidative Stress +15

Metformin attenuates lung fibrosis development via NOX4 suppression

Nahoko Sato, Naoki Takasaka, Masahiro Yoshida, +22

Respiratory Research

Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence

Hiromichi Hara, Jun Araya, Saburo Ito, +14

American Journal of Physiology-Lung Cellular and Molecular Physiology

Cell DeathMitochondrial BiologyOxidative StressDynamic OrganellesTobacco Control +16

Autophagy Induction by SIRT6 through Attenuation of Insulin-like Growth Factor Signaling Is Involved in the Regulation of Human Bronchial Epithelial Cell Senescence

Naoki Takasaka, Jun Araya, Hiromichi Hara, +21

The Journal of Immunology

MitophagyInflammatory Lung DiseaseLung InflammationAutophagy ActivationImmunology +18

Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis

Kenji Kobayashi, Jun Araya, Shunsuke Minagawa, +25

The Journal of Immunology

Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells

Naoki Takasaka, Robert Seed, Anthony Cormier, +17

JCI Insight

Role of IL-17A in murine models of COPD airway disease

Haruhiko Yanagisawa, Mitsuo Hashimoto, Shunsuke Minagawa, +9

American Journal of Physiology-Lung Cellular and Molecular Physiology

Pathogens in COPD exacerbations identified by comprehensive real-time PCR plus older methods

Kenichiro Shimizu, Yutaka Yoshii, Miyuki Morozumi, +20

International Journal of COPD