A. Szykowska

Structural analysis of human KDM5B guides histone demethylase inhibitor development

C. Johansson, Srikannathasan Velupillai, Anthony Tumber et al. · Nature Chemical Biology · 2016 · 198 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +10

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Anthony Tumber, Andrea Nuzzi, Edward S. Hookway et al. · Cell chemical biology · 2017 · 151 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

Álvaro Peña, Kamil Gewartowski, Seweryn Mroczek et al. · The EMBO Journal · 2012 · 107 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

8-Substituted Pyrido[3,4-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

Vassilios Bavetsias, Rachel M. Lanigan, G.F. Ruda et al. · Journal of Medicinal Chemistry · 2016 · 98 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates

Hanna Tarhonskaya, Radosław P. Nowak, C. Johansson et al. · Journal of Molecular Biology · 2017 · 42 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14