Cassandre Cavanaugh

GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Shannon E. Mullican, Xiefan Lin‐Schmidt, Chen‐Ni Chin et al. · Nature Medicine · 2017 · 755 citations

Life Sciences, Biochemistry, Endocrinology +4

Microbiota‐derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo

Matthew Jennis, Cassandre Cavanaugh, Gregory C. Leo et al. · Neurogastroenterology & Motility · 2017 · 168 citations

Life Sciences, Biochemistry, Immunology +17

Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents

Fuyong Du, Simon A. Hinke, Cassandre Cavanaugh et al. · Journal of Pharmacology and Experimental Therapeutics · 2018 · 31 citations · Full text

Medicine, Biochemistry, Pharmacology +15

Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice

Kamal Albarazanji, Matthew Jennis, Cassandre Cavanaugh et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2019 · 14 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15