David R. Webb

Discovery of Alogliptin:  A Potent, Selective, Bioavailable, and Efficacious Inhibitor of Dipeptidyl Peptidase IV

Jun Feng, Zhiyuan Zhang, Michael B. Wallace et al. · Journal of Medicinal Chemistry · 2007 · 404 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure.

Joseph P. Noon, Brian R. Walker, David R. Webb et al. · Journal of Clinical Investigation · 1997 · 328 citations · Full text

Life Sciences, Cardiology, Physiology +15

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

Qing Chen, Weilin Xie, Deborah J. Kuhn et al. · Blood · 2008 · 267 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation.

Brian R. Walker, A. A. Connacher, R M Lindsay et al. · The Journal of Clinical Endocrinology & Metabolism · 1995 · 266 citations

Medicine, Endocrinology, Pharmacology +15

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Derek F. Ceccarelli, Xiaojing Tang, Benoit Pelletier et al. · Cell · 2011 · 234 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12