Leslie A. Coonrod

Actinomycin D Specifically Reduces Expanded CUG Repeat RNA in Myotonic Dystrophy Models

Ruth B. Siboni, Masayuki Nakamori, Stacey D. Wagner et al. · Cell Reports · 2015 · 85 citations · Full text

Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA

Devika P. Gates, Leslie A. Coonrod, J. Andrew Berglund · Journal of Biological Chemistry · 2011 · 81 citations · Full text

Muscleblind-like 1, Transcriptional Regulation, Developmental Biology +14

Reducing Levels of Toxic RNA with Small Molecules

Leslie A. Coonrod, Masayuki Nakamori, Wenli Wang et al. · ACS Chemical Biology · 2013 · 81 citations · Full text

Methylene Linker Analogues, Toxic Rna, Medicine +13

Utilizing the GAAA Tetraloop/Receptor To Facilitate Crystal Packing and Determination of the Structure of a CUG RNA Helix

Leslie A. Coonrod, Jeremy R. Lohman, J. Andrew Berglund · Biochemistry · 2012 · 41 citations

Cug Helix, Protein Assembly, Biomolecular Structure Prediction +18

Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model

Elaine deLorimier, Leslie A. Coonrod, Jeremy Copperman et al. · Nucleic Acids Research · 2014 · 31 citations · Full text