Declan P. O’Regan

Anatomically Constrained Neural Networks (ACNNs): Application to Cardiac Image Enhancement and Segmentation

Ozan Oktay, Enzo Ferrante, Konstantinos Kamnitsas et al. · IEEE Transactions on Medical Imaging · 2017 · 724 citations · Full text

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease

Angharad M. Roberts, James S. Ware, Daniel S. Herman et al. · Science Translational Medicine · 2015 · 489 citations

Cardiac Muscle, Heart Failure, Cardiac Effects +20

Titin-truncating variants affect heart function in disease cohorts and the general population

Sebastian Schäfer, Antonio de Marvao, Eleonora Adami et al. · Nature Genetics · 2016 · 357 citations · Full text

Cardiomyopathy, Cardiovascular Disease, Disease Cohorts +8

Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy

Pablo García‐Pavía, Yuri Kim, María Alejandra Restrepo-Córdoba et al. · Circulation · 2019 · 329 citations · Full text

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients

Evangelos D. Michelakis, Vikram Gurtu, Linda Webster et al. · Science Translational Medicine · 2017 · 298 citations