Kenneth Siddle

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.

Yasuhiko Ebina, Eiichi Araki, M. Taira et al. · Proceedings of the National Academy of Sciences · 1987 · 397 citations · Full text

Insulin Receptor, Receptor Kinase Activity, Insulin Signaling +20

Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins

W. Sobey, Stephen Beer, C A Carrington et al. · Biochemical Journal · 1989 · 341 citations · Full text

Immunology, Glycobiology, 32-33 Split Proinsulin +20

Tumor Necrosis Factor-α Induces Apoptosis of Human Adipose Cells

Johannes B. Prins, Carola U. Niesler, Clay Winterford et al. · Diabetes · 1997 · 312 citations

Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

E M Bailyes, B. Nave, Maria A. Soos et al. · Biochemical Journal · 1997 · 280 citations · Full text

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

Peter R. Shepherd, B. Nave, Kenneth Siddle · Biochemical Journal · 1995 · 277 citations · Full text

Metabolic Syndrome, Glycogen Synthase, Signal Transduction +13