Rapidly produced SAM ^® vaccine against H7N9 influenza is immunogenic in mice

Armin Hekele, Sylvie Bertholet, Jacob Archer, +25

Emerging Microbes & Infections

CD81 Is a Central Regulator of Cellular Events Required for Hepatitis C Virus Infection of Human Hepatocytes

Michela Brazzoli, Alessia Bianchi, Sara Filippini, +4

Journal of Virology

ImmunologyContact AreasPathologyViral Structural ProteinCentral Regulator +19

Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin

Michela Brazzoli, Diletta Magini, Alessandra Bonci, +12

Journal of Virology

Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection

Gustavo Lou, Giulia Anderluzzi, S. Schmidt, +10

Journal of Controlled Release

NanoparticlesVaccinationNanomedicineCell-based Drug DeliveryEngineering +9

Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

Diletta Magini, Cinzia Giovani, Simona Mangiavacchi, +7

PLoS ONE

ImmunologyCd4 T Cell ResponsesFlu VaccinationInfluenza VaccinesCross-protection +14

Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines

Roshan Goswami, Despo Chatzikleanthous, Gustavo Lou, +11

ACS Infectious Diseases

The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency

Giulia Anderluzzi, Gustavo Lou, Stuart Woods, +8

Journal of Controlled Release

NanoparticlesVaccinationNanomedicineCross-protectionEngineering +8

Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection

Stefania Crotta, Michela Brazzoli, Diego Piccioli, +2

Journal of Hepatology

Host ResponseCytokine Environment PermissiveHepatitis CViral HepatitisImmunology +8

Folding and dimerization of hepatitis C virus E1 and E2 glycoproteins in stably transfected CHO cells

Michela Brazzoli, Ari Helenius, Steven K. H. Foung, +3

Virology

Virus StructureViral ReplicationMolecular VirologyViral HepatitisProtein Folding +9

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

Giulia Anderluzzi, Gustavo Lou, Simona Gallorini, +5

Vaccines