Leslie O. Ofori

Design of Protease Activated Optical Contrast Agents That Exploit a Latent Lysosomotropic Effect for Use in Fluorescence-Guided Surgery

Leslie O. Ofori, Nimali P. Withana, Tyler R. Prestwood et al. · ACS Chemical Biology · 2015 · 119 citations · Full text

Medicine, Cancer Biology, Oncology +17

Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes

Nimali P. Withana, Xiaowei Ma, Helen M. McGuire et al. · Scientific Reports · 2016 · 118 citations · Full text

Veterinary Medicine, Pathobiology, Pathology +17

From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

Leslie O. Ofori, Jason W. Hoskins, Masayuki Nakamori et al. · Nucleic Acids Research · 2012 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Design of a Highly Selective Quenched Activity-Based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization

Kristina Oresic Bender, Leslie O. Ofori, Wouter A. van der Linden et al. · Journal of the American Chemical Society · 2015 · 74 citations

Life Sciences, Biochemistry, Molecular Biology +14

Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion

Matthew A. Child, Carolyn I. Hall, Josh R. Beck et al. · Nature Chemical Biology · 2013 · 63 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14