Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models

Michael J. Daniels, Jack Rivers‐Auty, Tom Schilling, +22

Nature Communications

Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

Catherine Malaplate‐Armand, Sabrina Florent‐Béchard, Ihsen Youssef, +7

Neurobiology of Disease

Molecular NeuroscienceApoptosisSoluble OligomersAmyloid-β PeptideCell Death +7

Cytosolic phospholipase A ₂ mediates neuronal apoptosis induced by soluble oligomers of the amyloid‐β peptide

Badreddine Kriem, Isabelle Sponne, Alexandre Fifre, +8

The FASEB Journal

Bilirubin Induces Apoptosis via Activation of NMDA Receptors in Developing Rat Brain Neurons

Stéphanie Grojean, Violette Koziel, P Vert, +1

Experimental Neurology

Rat Brain NeuronsMedicineApoptosisNmda ReceptorsCell Death +8

Ciliary Neurotrophic Factor Cell-Based Delivery Prevents Synaptic Impairment and Improves Memory in Mouse Models of Alzheimer's Disease

Pierre Garcia, Ihsen Youssef, Jo Kristian Utvik, +16

Journal of Neuroscience

Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid‐β oligomers

Sabrina Florent, Catherine Malaplate‐Armand, Ihsen Youssef, +9

Journal of Neurochemistry

Microtubule-associated Protein MAP1A, MAP1B, and MAP2 Proteolysis during Soluble Amyloid β-Peptide-induced Neuronal Apoptosis

Alexandre Fifre, Isabelle Sponne, Violette Koziel, +6

Journal of Biological Chemistry

ApoptosisMicrotubule PerturbationCell DeathMicrotubule-associated Protein Map1aCytoskeleton +20

Apoptotic Neuronal Cell Death Induced by the Non-fibrillar Amyloid-β Peptide Proceeds through an Early Reactive Oxygen Species-dependent Cytoskeleton Perturbation

Isabelle Sponne, Alexandre Fifre, Béatrice Drouet, +6

Journal of Biological Chemistry

Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of the amyloid‐β peptide

Isabelle Sponne, Alexandre Fifre, Badreddine Kriem, +5

The FASEB Journal

Proteinlipid InteractionCell DeathLipid MovementAmyloid‐β PeptideCholesterol Protection +17

Homocysteinylation of neuronal proteins contributes to folate deficiency‐associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells

Nassila Akchiche, Carine Bossenmeyer‐Pourié, Racha Kerek, +10

The FASEB Journal

Epigenetic ChangeSynaptic TransmissionMethyl Donor FolateCellular NeurobiologySynaptic Signaling +19