Caroline Granycome

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

Henna Tyynismaa, Hiroshi Sembongi, Monika Bokori-Brown et al. · Human Molecular Genetics · 2004 · 244 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization

Jiuya He, Chih-Chieh Mao, Aurelio Reyes et al. · The Journal of Cell Biology · 2007 · 241 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication

Javier Miralles Fusté, Sjoerd Wanrooij, Elisabeth Jemt et al. · Molecular Cell · 2010 · 218 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Klaus Klumpp, Vincent Lévêque, Sophie Le Pogam et al. · Journal of Biological Chemistry · 2005 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

David B. Smith, Joseph A. Martin, Klaus Klumpp et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 97 citations

Pharmacy, Biochemistry, Medicinal Chemistry +16