Melanie Trusselle

Chiral Aromatase and Dual Aromatase−Steroid Sulfatase Inhibitors from the Letrozole Template: Synthesis, Absolute Configuration, and In Vitro Activity

Paul M. Wood, L. W. Lawrence Woo, Jean‐Robert Labrosse et al. · Journal of Medicinal Chemistry · 2008 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Dual aromatase–sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity

Toby Jackson, L. W. Lawrence Woo, Melanie Trusselle et al. · Organic & Biomolecular Chemistry · 2007 · 60 citations

Life Sciences, Oncology, Pharmacology +17

Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, <i>in vitro</i> and <i>in vivo</i> activities, molecular modeling, and protein crystallography

L. W. Lawrence Woo, Delphine S. Fischer, Christopher M. Sharland et al. · Molecular Cancer Therapeutics · 2008 · 41 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14

Non‐Steroidal Aromatase Inhibitors Based on a Biphenyl Scaffold: Synthesis, in vitro SAR, and Molecular Modelling

Toby Jackson, L. W. Lawrence Woo, Melanie Trusselle et al. · ChemMedChem · 2008 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

<i>scyllo</i>‐Inositol Pentakisphosphate as an Analogue of <i>myo</i>‐Inositol 1,3,4,5,6‐Pentakisphosphate: Chemical Synthesis, Physicochemistry and Biological Applications

Andrew M. Riley, Melanie Trusselle, Paul Kuad et al. · ChemBioChem · 2006 · 29 citations · Full text

Life Sciences, Biochemistry, Cell Biology +11