Karina Calvopiña

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

Alen Krajnc, Jürgen Brem, Philip Hinchliffe et al. · Journal of Medicinal Chemistry · 2019 · 195 citations · Full text

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Jürgen Brem, Tharindi Panduwawala, Jon Hansen et al. · Nature Chemistry · 2021 · 77 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Antimicrobial Drug Discovery +11

Structural and Kinetic Studies of the Potent Inhibition of Metallo-β-lactamases by 6-Phosphonomethylpyridine-2-carboxylates

Philip Hinchliffe, Carol A. Tanner, Anthony P. Krismanich et al. · Biochemistry · 2018 · 59 citations · Full text

Structural/mechanistic insights into the efficacy of nonclassical β‐lactamase inhibitors against extensively drug resistant <i>Stenotrophomonas maltophilia</i> clinical isolates

Karina Calvopiña, Philip Hinchliffe, Jürgen Brem et al. · Molecular Microbiology · 2017 · 49 citations · Full text

Antimicrobial Chemotherapy, Antibiotic Resistance, Bacterial Pathogens +24

Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

Pauline A. Lang, Anete Parkova, T.M. Leissing et al. · Biomolecules · 2020 · 32 citations · Full text