Rana Alaaeddine

Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study

Ghandoura Moussa, Rana Alaaeddine, Lynn M. Alaeddine et al. · European Journal of Medicinal Chemistry · 2017 · 84 citations · Full text

Medicinal Chemistry, Anti-inflammatory Agents, Medicine +9

Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases

Perihan A. Elzahhar, Shrouk M. Abd El Wahab, Mohamed Elagawany et al. · European Journal of Medicinal Chemistry · 2020 · 76 citations · Full text

Tumor-associated Carbonic Anhydrases, Medicinal Chemistry, Biochemistry +9

Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones

Perihan A. Elzahhar, Rana Alaaeddine, Tamer M. Ibrahim et al. · European Journal of Medicinal Chemistry · 2019 · 49 citations · Full text

Inflammation, Drug Targeting, Anti-inflammatory +10

Impaired Endothelium-Dependent Hyperpolarization Underlies Endothelial Dysfunction during Early Metabolic Challenge: Increased ROS Generation and Possible Interference with NO Function

Rana Alaaeddine, Mohammed A.W. Elkhatib, Ali Mroueh et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 32 citations · Full text

The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs)

Rana Alaaeddine, Perihan A. Elzahhar, Ibrahim AlZaim et al. · Current Medicinal Chemistry · 2020 · 20 citations

15-Lox Activities, Arachidonic Acid Metabolism, Lipid Peroxidation +22