Christopher M. Mapes

Biological Characterization of a Heterodimer-Selective Retinoid X Receptor Modulator: Potential Benefits for the Treatment of Type 2 Diabetes

Mark D. Leibowitz, Robert Ardecky, Marcus F. Boehm et al. · Endocrinology · 2005 · 70 citations · Full text

Medicine, Endocrinology, Pharmacology +15

Novel (2<i>E</i>,4<i>E</i>,6<i>Z</i>)-7-(2-Alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic Acid Retinoid X Receptor Modulators Are Active in Models of Type 2 Diabetes

Pierre‐Yves Michellys, Robert Ardecky, J. H. Chen et al. · Journal of Medicinal Chemistry · 2003 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Reactions between Weinreb Amides and 2-Magnesiated Oxazoles:  A Simple and Efficient Preparation of 2-Acyl Oxazoles

Daniel J. Pippel, Christopher M. Mapes, Neelakandha S. Mani · The Journal of Organic Chemistry · 2007 · 38 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Design, Synthesis, and Structure−Activity Relationship Studies of Novel 6,7-Locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic Acids

Pierre‐Yves Michellys, Robert Ardecky, Jyun‐Hung Chen et al. · Journal of Medicinal Chemistry · 2003 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design and synthesis of novel RXR-selective modulators with improved pharmacological profile

Pierre‐Yves Michellys, Marcus F. Boehm, Jyun‐Hung Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11