Lukáš Bálek

Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation

Pavel Krejčı́, Anie Aklian, Markéta Kaucká et al. · PLoS ONE · 2012 · 164 citations · Full text

Molecular Regulation, Direct β-Catenin Phosphorylation, Synaptic Signaling +19

Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes

Iva Gudernová, Iva Veselá, Lukáš Bálek et al. · Human Molecular Genetics · 2015 · 67 citations · Full text

Multikinase Activity, Fgfr Tkis, Pathology +16

Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

Marcela Buchtová, Veronika Oralová, Anie Aklian et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2015 · 60 citations

Developmental Biology, Bone Morphogenic Protein, Medicine +10

An inactivating mutation in intestinal cell kinase,<i>ICK</i>, impairs hedgehog signalling and causes short rib-polydactyly syndrome

S. Paige Taylor, Michaela Kunova Bosakova, Miroslav Vařecha et al. · Human Molecular Genetics · 2016 · 58 citations · Full text

Genetics, Pathology, Molecular Genetics +23

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

Bohumil Fafílek, Lukáš Bálek, Michaela Kunova Bosakova et al. · Science Signaling · 2018 · 56 citations · Full text