Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

Nobuhiko Katunuma, E. Murata, Hisao Kakegawa, +7

FEBS Letters

Expression of programmed death 1 (PD-1) and its ligand (PD-L1) in thymic epithelial tumors: Impact on treatment efficacy and alteration in expression after chemotherapy

Yuki Katsuya, Hidehito Horinouchi, Tetsuhiko Asao, +9

Lung Cancer

Lysosomal cathepsin B plays an important role in antigen processing, while cathepsin D is involved in degradation of the invariant chain in
ovalbumin‐immunized mice

T. Zhang, Yoichi Maekawa, J. Hanba, +8

Immunology

The genomic and epigenomic landscape in thymic carcinoma

Motonobu Saito, Yutaka Fujiwara, Tetsuhiko Asao, +8

Carcinogenesis

EngineeringGeneticsPathologyThymic CarcinomaEpigenetics +14

Pemetrexed for advanced non-small cell lung cancer patients with interstitial lung disease

Motoyasu Kato, Takehito Shukuya, Fumiyuki Takahashi, +11

BMC Cancer

Arg-Gingipain Is Responsible for the Degradation of Cell Adhesion Molecules of Human Gingival Fibroblasts and Their Death Induced by Porphyromonas gingivalis

A. Baba, Naoko Abe, Tomoko Kadowaki, +4

Biological Chemistry

Cell AdhesionImmunologyCell DeathCell Adhesion MoleculesOral Microbiology +17

Genetic and enzymatic evidence for Lewis enzyme expression in Lewis-negative cancer patients.

Shin Yazawa, Shoko Nishihara, Hiroko Iwasaki, +4

PubMed

ImmunologyBlood CellPathologyCancer PatientsHematological Malignancy +17

Activation of insulin‐like growth factor‐1 receptor confers acquired resistance to osimertinib in non‐small cell lung cancer with <i>EGFR</i> T790M mutation

Daisuke Hayakawa, Fumiyuki Takahashi, Yoichiro Mitsuishi, +17

Thoracic Cancer

Roles for Arg- and Lys-Gingipains in the Disruption of Cytokine Responses and Loss of Viability of Human Endothelial Cells by Porphyromonas gingivalis Infection

Atsuyo Baba, Tomoko Kadowaki, Tetsuhiko Asao, +1

Biological Chemistry

Extracellular vesicles and particles as mediators of long-range communication in cancer: connecting biological function to clinical applications

Tetsuhiko Asao, Gabriel Cardial Tobias, Serena Lucotti, +3

Extracellular Vesicles and Circulating Nucleic Acids

PathologyExtracellular MicrovesiclesSystemic EvpsTumor BiologyOncology +19