Imran G. House

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade

Imran G. House, Peter Savas, Junyun Lai et al. · Clinical Cancer Research · 2019 · 766 citations

Medicine, Immunology, Oncology +17

Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity

Junyun Lai, Sherly Mardiana, Imran G. House et al. · Nature Immunology · 2020 · 215 citations

Life Sciences, Immunology, Oncology +17

FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy

Jack D. Chan, C. Scheffler, Isabelle Munoz et al. · Nature · 2024 · 214 citations · Full text

Life Sciences, Immunology, Oncology +16

CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy

Lauren Giuffrida, Kevin Sek, Melissa A. Henderson et al. · Nature Communications · 2021 · 210 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

Lauren Giuffrida, Kevin Sek, Melissa A. Henderson et al. · Molecular Therapy · 2020 · 107 citations · Full text

Life Sciences, Immunology, Oncology +17