Kevin Sek

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade

Imran G. House, Peter Savas, Junyun Lai et al. · Clinical Cancer Research · 2019 · 689 citations

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida et al. · Journal of Clinical Investigation · 2017 · 309 citations · Full text

Chimeric Antigen Receptor, Cancer Immunosurveillance, Signal Transduction +15

Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity

Junyun Lai, Sherly Mardiana, Imran G. House et al. · Nature Immunology · 2020 · 207 citations

Tumor Immunology, Cancer Immunosurveillance, T Cells +11

CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy

Lauren Giuffrida, Kevin Sek, Melissa A. Henderson et al. · Nature Communications · 2021 · 194 citations · Full text

FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy

Jack D. Chan, C. Scheffler, Isabelle Munoz et al. · Nature · 2024 · 176 citations · Full text