Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats

Ahmed E. Khodir, Eman Said, Hoda Atif, +2

Biomedicine & Pharmacotherapy

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition

Sameh Saber, Eslam E. Abd El-Fattah, Galal Yahya, +15

Pharmaceuticals

The protective effect of Lactobacillus versus 5-aminosalicylic acid in ulcerative colitis model by modulation of gut microbiota and Nrf2/Ho-1 pathway

Ahmed M. El-Baz, Ahmed E. Khodir, Mohamed Mohamed Adel El‐Sokkary, +1

Life Sciences

InflammationProbioticDysbiosisMicrobiotaGut Microbiology +12

β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: rational based design,<i>in silico</i>,<i>in vitro</i>, and SAR studies for lead optimization

Khaled M. Darwish, Raya Soltane, Amani Chrouda, +7

RSC Advances

Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids

Ahmed A.E. Mourad, Ahmed E. Khodir, Sameh Saber, +1

Pharmaceuticals

Implication of Nrf2/HO-1 pathway in the coloprotective effect of coenzyme Q10 against experimentally induced ulcerative colitis

Ahmed E. Khodir, Hoda Atef, Eman Said, +2

Inflammopharmacology

InflammationCoenzyme Q10ImmunologyPathologyGut Barrier +5

Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression

Sameh Saber, Mohamed Nasr, Ahmed S. Saad, +16

Biomedicine & Pharmacotherapy

Albendazole-loaded CubosomesNanotherapeuticsChemoprevention StrategyHepatocellular Carcinoma ProgressionCancer Biology +18

Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy

Abdallah M. Gendy, Mohamed R. Elnagar, Mona M. Allam, +6

Biomedicine & Pharmacotherapy

A novel role of nifuroxazide in attenuation of sepsis-associated acute lung and myocardial injuries; role of TLR4/NLPR3/IL-1β signaling interruption

Ahmed E. Khodir, Yara A. Samra, Eman Said

Life Sciences

InflammationAcute Lung InjuryMyocardial InjuriesAnti-inflammatoryLung Inflammation +8

RETRACTED: Phenethyl isothiocyanate attenuates diabetic nephropathy via modulation of glycative/oxidative/inflammatory signaling in diabetic rats

Nada H. Eisa, Ahmed E. Khodir, Mohamed El‐Sherbiny, +2

Biomedicine & Pharmacotherapy