The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation

Somayeh S. Tarighat, Ramasamy Santhanam, David Frankhouser, +14

Leukemia

Histone ModificationsChromatinHistone Arginine MethylationChromatin RemodelingEpigenetic Change +11

Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia

William Blum, Sebastian Schwind, Somayeh S. Tarighat, +20

Blood

B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3

Fei Fei, Eun Ji Joo, Somayeh S. Tarighat, +6

Oncotarget

Stromal CellsHematological MalignancyCell RegulationCell InteractionMalignant Blood Disorder +13

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Soyoung Oh, Kate Senger, Shravan Madireddi, +7

The Journal of Experimental Medicine

EngineeringImmunologyImmune Cell TherapyImmunotherapyT Cells +17

Sunflower ( <i>Helianthus annuus</i> L.) as a pre-Columbian domesticate in Mexico

David L. Lentz, Mary Pohl, José Luis Alvarado, +2

Proceedings of the National Academy of Sciences

Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia

Alice S. Mims, Alison R. Walker, Xiaomeng Huang, +20

Leukemia

Hematological MalignancyNovel Epigenetic-targeting ApproachAnti-leukemic ActivityMixed-phenotype Acute LeukemiaAcute Myeloid Leukemia +7

Targeting the RAS/MAPK pathway with<i>miR-181a</i>in acute myeloid leukemia

Xiaomeng Huang, Sebastian Schwind, Ramasamy Santhanam, +15

Oncotarget

Cancer ResearchLower Mir-181a ExpressionMedicineAcute Myeloid LeukemiaAml Growth +9

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

Houda Alachkar, Ramasamy Santhanam, Kati Maharry, +28

Journal of Clinical Investigation

Leukemic Cell GrowthMixed-phenotype Acute LeukemiaImmunologyPathologyCancer Biology +19

Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology

Kwame Okrah, Somayeh S. Tarighat, Bo Liu, +16

npj Precision Oncology

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms

Joseph Castillo, Esther Wu, Christopher Lowe, +20

Cancer Research