Concepedia
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Publications
20
Citations
2.1K
H-Index
17
Active since
2010
Affiliations
Scripps Research Institute(Current)
University of California San Diego
Tel Aviv University
Scintillon Institute
Discovery Institute
Dorit Trudler is an author at Scripps Research Institute specializing in medicine, neuroscience, and neurology.
Top concepts
MedicineNeuroscienceNeurologyNeurodegenerationAlzheimer's DiseaseNeurodegenerative DiseasesNeuroprotectionNeuropharmacologyCell DeathImmunology
Publications per year
2010–2024
Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria
Lihi Adler‐Abramovich, Lilach Vaks, Ohad Carny et al. · Nature Chemical Biology · 2012 · 455 citations
Phenylalanine Assembly, Alzheimer's Disease, Biochemistry +6
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
Hongxu Xian, Yuan Liu, A. Nilsson et al. · Immunity · 2021 · 369 citations · Full text
Inflammation, Mitochondrial Atp, Anti-inflammatory +12
Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls
Swagata Ghatak, Nima Dolatabadi, Dorit Trudler et al. · eLife · 2019 · 225 citations · Full text
Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia
Dorit Trudler, Kristopher L. Nazor, Yvonne S. Eisele et al. · Proceedings of the National Academy of Sciences · 2021 · 129 citations · Full text
<scp>DJ</scp>‐1 deficiency triggers microglia sensitivity to dopamine toward a pro‐inflammatory phenotype that is attenuated by rasagiline
Dorit Trudler, Orly Weinreb, Silvia Mandel et al. · Journal of Neurochemistry · 2013 · 115 citations
Oxidative Stress Sensor, Immunology, Cell Death +21
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