Concepedia

Author

Silvia Mandel

Technion – Israel Institute of Technology

Also Known As

S MANDEL, S Mandel, S. MANDEL, S. Mandel, S.A. Mandel, SILVIA MANDEL, Silvia A Mandel, Silvia A. Mandel, Silvia Mandel

144

Publications

11.6K

Citations

55

H-Index

96

Concepts

All Affiliations

Technion – Israel Institute of TechnologyRappaport Family Institute for Research in the Medical SciencesFoundation CenterFamily Research InstituteParkinson's Foundation
SM

About

Silvia Mandel is an author at Technion – Israel Institute of Technology specializing in medicine, neuroprotection, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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Social Sciences

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Biochemistry

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Natural Sciences

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Health Sciences

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Silvia Mandel

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57

Publications

5.7K

Citations

38

H-Index

YearCitations

Green tea polyphenol (–)‐epigallocatechin‐3‐gallate prevents <i>N</i>‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced dopaminergic neurodegeneration

Yona Levites, Orly Weinreb, Gila Maor,

Journal of Neurochemistry

2001

563

Involvement of Protein Kinase C Activation and Cell Survival/ Cell Cycle Genes in Green Tea Polyphenol (−)-Epigallocatechin 3-Gallate Neuroprotective Action

Yona Levites, Tamar Amit, Moussa B. H. Youdim,

Journal of Biological Chemistry

2002

415

Neuroprotection and neurorescue against Aβ toxicity and PKC‐dependent release of non‐amyloidogenic soluble precursor protein by green tea polyphenol (‐)‐epigallocatechin‐3‐gallate

Yona Levites, Tamar Amit, Silvia Mandel,

The FASEB Journal

2003

373

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

E. Gr�nblatt, Silvia Mandel, Jasmine Jacob‐Hirsch,

Journal of Neural Transmission

2004

357

Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-κB) activation and cell death by tea extracts in neuronal cultures11Abbreviations: BT, Black Tea; EMSA, Electromobility Shift Assay; EGCG, (-)-Epigallocatechin-3-gallate; GT, Green Tea; NB SH-SY5Y cells, Human neuroblastoma SH-SY5Y cells; 6-OHDA, 6-hydroxydopamine; IL, Interleukin; LDH, Lactate Dehydrogenase; MPTP, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NF-κB, nuclear factor-κB; OS, Oxidative Stress; PD, Parkinson’s Disease; ROS, Reactive Oxygen Species; SNPC, Substantia Nigra Pars Compacta; TBARS, thiobarbituric acid reactive substances.

Yona Levites, Moussa B. H. Youdim, Gila Maor,

Biochemical Pharmacology

2002

292

Gene expression analysis in <i>N</i>‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of <i>R</i>‐apomorphine

Edna Grünblatt, Silvia Mandel, Gila Maor,

Journal of Neurochemistry

2001

246

Neuroprotective molecular mechanisms of (−)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties

Orly Weinreb, Tamar Amit, Silvia Mandel,

Genes & Nutrition

2009

239

Reduction of iron‐regulated amyloid precursor protein and β‐amyloid peptide by (–)‐epigallocatechin‐3‐gallate in cell cultures: implications for iron chelation in Alzheimer's disease

Lydia Reznichenko, Tamar Amit, Hailin Zheng,

Journal of Neurochemistry

2006

187

Iron and α-Synuclein in the Substantia Nigra of MPTP-Treated Mice: Effect of Neuroprotective Drugs R-Apomorphine and Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate

Silvia Mandel, Gila Maor, Moussa B. H. Youdim

Journal of Molecular Neuroscience

2004

169

Green tea polyphenol (–)‐epigallocatechin‐3‐gallate induces neurorescue of long‐term serum‐deprived PC12 cells and promotes neurite outgrowth

Lydia Reznichenko, Tamar Amit, Moussa B. H. Youdim,

Journal of Neurochemistry

2005

149

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