Kevin O. Tankersley

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.

William Lewis, Eric S. Levine, B. Griniuvienė et al. · Proceedings of the National Academy of Sciences · 1996 · 164 citations

Life Sciences, Biochemistry, Genetics +17

Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii

Max H. Iltzsch, Sheri S. Uber, Kevin O. Tankersley et al. · Biochemical Pharmacology · 1995 · 68 citations

Life Sciences, Chemical Biology, Molecular Biology +16

Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids

Corie A. Ellison, Kevin O. Tankersley, Cindy Obringer et al. · Toxicology in Vitro · 2020 · 66 citations · Full text

Pharmacy, Dermatology, Pharmacokinetics +13

Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax).

William Lewis, B. Griniuvienė, Kevin O. Tankersley et al. · PubMed · 1997 · 59 citations

Life Sciences, Biology, Genetics +9

Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii

Max H. Iltzsch, Kevin O. Tankersley · Biochemical Pharmacology · 1994 · 37 citations

Life Sciences, Biochemistry, Molecular Biology +13