Brian A. Wadugu

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

Cara Lunn Shirai, James N. Ley, Brian S. White et al. · Cancer Cell · 2015 · 284 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Moderate and high amounts of tamoxifen in <i>α-MHC-MerCreMer</i> mice induce a DNA damage response, leading to heart failure and death

Kevin Bersell, Sangita Choudhury, Mariya Mollova et al. · Disease Models & Mechanisms · 2013 · 147 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring <i>SF3B1</i> or <i>U2AF1</i> Mutations

Abigael Cheruiyot, Shan Li, Sridhar Nonavinkere Srivatsan et al. · Cancer Research · 2021 · 60 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice

Brian A. Wadugu, Sridhar Nonavinkere Srivatsan, Amanda Heard et al. · Journal of Clinical Investigation · 2021 · 19 citations · Full text

Medicine, Genetics, Oncology +11

DNA Interstrand Cross-Linking Activity of (1-Chloroethenyl)oxirane, a Metabolite of β-chloroprene

Brian A. Wadugu, Christopher Ng, Bethany L. Bartley et al. · Chemical Research in Toxicology · 2009 · 14 citations

Pharmacy, Biochemistry, Toxicology +17