MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

Su Jung Song, Laura Poliseno, Min Sup Song, +9

Cell

Tet-family-dependent ChromatinMedicineStem CellsBreast CancerMicrorna Detection +6

Detection of long repeat expansions from PCR-free whole-genome sequence data

Egor Dolzhenko, Joke J.F.A. van Vugt, Richard J. Shaw, +40

Genome Research

The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo

Florian A. Karreth, Markus Reschke, Anna Ruocco, +20

Cell

Braf Pseudogene FunctionsImmunologyRna BiologyCompetitive Endogenous RnaLong Non-coding Rna +8

Fatty acid synthesis is required for breast cancer brain metastasis

Gino B. Ferraro, Ahmed Ali, Alba Luengo, +33

Nature Cancer

BiochemistryFatty Acid SynthesisBreast CancerMetabolic RemodelingRadiation Oncology +1

An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer

Ming Chen, Jiangwen Zhang, Katia Sampieri, +20

Nature Genetics

Prostatic DiseaseCell BiologyLipid Synthesis

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

Antonella Papa, Lixin Wan, Massimo Bonora, +16

Cell

Signal TransductionSignaling PathwayCell RegulationMedicineDominant-negative Manner +7

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Ryan G. Lim, Lisa Salazar, Daniel K. Wilton, +48

Nature Neuroscience

NeuroregenerationDevelopmental BiologyMolecular NeuroscienceDevelopmental AlterationsMedicine +11

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

Michael A. Lodato, Christopher Ng, Joseph A. Wamstad, +5

PLoS Genetics

Transcriptional RegulationSpecify Cell StateDevelopmental BiologyCell LineageLineage Plasticity +13

Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms

Marco Bezzi, Nina Seitzer, T. Ishikawa, +11

Nature Medicine

Distinct MechanismsImmunogeneticsImmune EvasionTumor ImmunologyCancer Immunosurveillance +9

Targeting H3K4 trimethylation in Huntington disease

Malini Vashishtha, Christopher Ng, Ferah Yildirim, +17

Proceedings of the National Academy of Sciences