Ileana Corvo

AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach, Denzil Bernard, Kong T. Nguyen et al. · Scientific Reports · 2024 · 120 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +16

Collagenolytic Activities of the Major Secreted Cathepsin L Peptidases Involved in the Virulence of the Helminth Pathogen, Fasciola hepatica

Mark W. Robinson, Ileana Corvo, Peter M. Jones et al. · PLoS neglected tropical diseases · 2011 · 87 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen

Ileana Corvo, Martín Cancela, Mónica Cappetta et al. · Molecular and Biochemical Parasitology · 2009 · 73 citations

Life Sciences, Biochemistry, Pathology +8

Identification of Chalcones as Fasciola hepatica Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach

Florencia Ferraro, Alicia Merlino, Nicolás dell ́Oca et al. · PLoS neglected tropical diseases · 2016 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica

Ileana Corvo, Anthony J. O’Donoghue, Lucía Pastro et al. · PLoS neglected tropical diseases · 2013 · 31 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +16