Timothy S. Charlebois

Microarray and proteomics expression profiling identifies several candidates, including the valosin‐containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines

Padraig Doolan, Paula Meleady, Niall Barron et al. · Biotechnology and Bioengineering · 2010 · 83 citations

Life Sciences, Biochemistry, Molecular Biology +17

The manufacturing process for recombinant factor IX.

Scott H. Harrison, S. Robert Adamson, D Bonam et al. · Seminars in Hematology · 1998 · 65 citations

Engineering, Bioengineering, Biotechnology +8

CHO DUKX cell lineages preadapted to growth in serum-free suspension culture enable rapid development of cell culture processes for the manufacture of recombinant proteins

Martin S. Sinacore, Timothy S. Charlebois, Scott H. Harrison et al. · Biotechnology and Bioengineering · 1996 · 53 citations

Life Sciences, Biotechnology, Molecular Biology +17

Proteomic profiling of CHO cells with enhanced rhBMP‐2 productivity following co‐expression of PACEsol

Paula Meleady, Michael Henry, Patrick Gammell et al. · PROTEOMICS · 2008 · 51 citations

Life Sciences, Biochemistry, Molecular Biology +13

Transcriptional Profiling of Gene Expression Changes in a PACE-Transfected CHO DUKX Cell Line Secreting High Levels of rhBMP-2

Padraig Doolan, Mark Melville, Patrick Gammell et al. · Molecular Biotechnology · 2008 · 44 citations

Life Sciences, Genetics, Molecular Biology +4