Martin S. Sinacore

Adaptation of Mammalian Cells to Growth in Serum-Free Media

Martin S. Sinacore, Denis Drapeau, S. Robert Adamson · Molecular Biotechnology · 2000 · 127 citations

Medicine, Cell Culture, Cell Proliferation +4

Microarray and proteomics expression profiling identifies several candidates, including the valosin‐containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines

Padraig Doolan, Paula Meleady, Niall Barron et al. · Biotechnology and Bioengineering · 2010 · 83 citations

Cell Culture, Cell Proliferation, Cell Growth +19

CHO DUKX cell lineages preadapted to growth in serum-free suspension culture enable rapid development of cell culture processes for the manufacture of recombinant proteins

Martin S. Sinacore, Timothy S. Charlebois, Scott H. Harrison et al. · Biotechnology and Bioengineering · 1996 · 53 citations

Embryonic Stem Cell, Recombinant Proteins, Induced Pluripotent Stem Cell +14

Proteomic profiling of CHO cells with enhanced rhBMP‐2 productivity following co‐expression of PACEsol

Paula Meleady, Michael Henry, Patrick Gammell et al. · PROTEOMICS · 2008 · 51 citations

Sclerostin, Molecular Biology, Enhanced Rhbmp‐2 Productivity +19

Transcriptional Profiling of Gene Expression Changes in a PACE-Transfected CHO DUKX Cell Line Secreting High Levels of rhBMP-2

Padraig Doolan, Mark Melville, Patrick Gammell et al. · Molecular Biotechnology · 2008 · 44 citations

Transcriptional Profiling, Signal Transduction, Signaling Pathway +9