Kouichiro Goto

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-β (transforming growth factor-β) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-β type I receptor

Go Kuratomi, Akiyoshi Komuro, Kouichiro Goto et al. · Biochemical Journal · 2005 · 217 citations

Life Sciences, Cell Biology, Molecular Biology +14

Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

Masahito Kawazu, Kayoko Saso, Kit I. Tong et al. · PLoS ONE · 2011 · 200 citations · Full text

Medicine, Cancer Biology, Molecular Biology +17

Ki26894, a novel transforming growth factor‐β type I receptor kinase inhibitor, inhibits <i>in vitro</i> invasion and <i>in vivo</i> bone metastasis of a human breast cancer cell line

Shogo Ehata, Aki Hanyu, Μakoto Fujime et al. · Cancer Science · 2006 · 182 citations · Full text

Medicine, Cancer Biology, Oncology +17

Selective Inhibitory Effects of Smad6 on Bone Morphogenetic Protein Type I Receptors

Kouichiro Goto, Yuto Kamiya, Takeshi Imamura et al. · Journal of Biological Chemistry · 2007 · 144 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Chromosomal Region Maintenance 1 (CRM1)-dependent Nuclear Export of Smad Ubiquitin Regulatory Factor 1 (Smurf1) Is Essential for Negative Regulation of Transforming Growth Factor-β Signaling by Smad7

Yoshitaka Tajima, Kouichiro Goto, Minoru Yoshida et al. · Journal of Biological Chemistry · 2003 · 92 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13