Concepedia

Yaogeng Wang

YW

Statistics

Publications

14

Citations

259

H-Index

10

Active since

2018

Affiliations

The Netherlands Cancer Institute(Current)

Utrecht University

Oncode Institute

Slotervaartziekenhuis

Yaogeng Wang is an author at The Netherlands Cancer Institute specializing in medicine, pharmacology, and pharmacotherapy.

Top concepts

Publications per year

2018–2023

14

Publications

14

P‐glycoprotein (MDR1/ABCB1) restricts brain accumulation and cytochrome P450‐3A (CYP3A) limits oral availability of the novel ALK/ROS1 inhibitor lorlatinib

Wenlong Li, Rolf W. Sparidans, Yaogeng Wang et al. · International Journal of Cancer · 2018 · 41 citations · Full text

P-glycoprotein and breast cancer resistance protein restrict brigatinib brain accumulation and toxicity, and, alongside CYP3A, limit its oral availability

Wenlong Li, Rolf W. Sparidans, Yaogeng Wang et al. · Pharmacological Research · 2018 · 34 citations · Full text

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Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism

Changpei Gan, Jing Wang, Alejandra Martínez-Chávez et al. · Acta Pharmaceutica Sinica B · 2022 · 29 citations · Full text

OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation

Yaogeng Wang, Rolf W. Sparidans, Wenlong Li et al. · British Journal of Pharmacology · 2020 · 24 citations · Full text

Oral coadministration of elacridar and ritonavir enhances brain accumulation and oral availability of the novel ALK/ROS1 inhibitor lorlatinib

Wenlong Li, Rolf W. Sparidans, Yaogeng Wang et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2019 · 22 citations

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1–5 of 14