Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

Zewen Jiang, Meng Zhao, Laëtitia Voilquin, +17

Cell Metabolism

ObesityMetabolic SyndromeGlucose ToleranceMetabolic DisorderMedicine +9

Arresten, a Collagen-Derived Angiogenesis Inhibitor, Suppresses Invasion of Squamous Cell Carcinoma

Mari Aikio, Ilkka Alahuhta, Sini Nurmenniemi, +9

PLoS ONE

Squamous Cell CarcinomaCell ProliferationCancer BiologyTumor BiologyTumor Angiogenesis +19

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

Mari Aikio, Harri Elamaa, David Vicente, +15

Proceedings of the National Academy of Sciences

Basement Membrane Zone Collagens XV and XVIII/Proteoglycans Mediate Leukocyte Influx in Renal Ischemia/Reperfusion

Azadeh Zaferani, D. Talsma, Saleh Yazdani, +6

PLoS ONE

Renal PathologyImmunologyRenal InflammationType XvCellular Physiology +21

Collagen XVIII Short Isoform Is Critical for Retinal Vascularization, and Overexpression of the Tsp-1 Domain Affects Eye Growth and Cataract Formation

Mari Aikio, Merja Hurskainen, Gaëlle Brideau, +5

Investigative Ophthalmology & Visual Science

Lack of collagen XVIII leads to lipodystrophy and perturbs hepatic glucose and lipid homeostasis

Tiina Petäistö, David Vicente, Kari A. Mäkelä, +11

The Journal of Physiology

Endostatin induces proliferation of oral carcinoma cells but its effect on invasion is modified by the tumor microenvironment

Ilkka Alahuhta, Mari Aikio, Otto Väyrynen, +7

Experimental Cell Research

MedicineImmunologyBiological MicroenvironmentsCancer GrowthOral Carcinoma Cells +6

Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis

Niko Kivinen, Szabolcs Felszeghy, Aino I. Kinnunen, +7

Biogerontology

Ocular DiseaseOphthalmologyExperimental OphthalmologyCollagen XviiiCellular Senescence +4

Matrix metalloproteinase 9 inhibits the motility of highly aggressive HSC-3 oral squamous cell carcinoma cells

Otto Väyrynen, Pirjo Åström, Pia Nyberg, +8

Experimental Cell Research

Tumor BiologyMalignant DiseaseOncogenic AgentMedicinePathology +5

Opposing roles of p38α-mediated phosphorylation and arginine methylation in driving TDP-43 proteinopathy

Mari Aikio, Heike J. Wobst, Hana M. Odeh, +18