Donald J. Vander Griend

Glucocorticoid Receptor Activity Contributes to Resistance to Androgen-Targeted Therapy in Prostate Cancer

Masis Isikbay, Kristen Otto, Steven Kregel et al. · Hormones and Cancer · 2014 · 274 citations · Full text

Urology, Medicine, Androgen-targeted Therapy +6

The Role of CD133 in Normal Human Prostate Stem Cells and Malignant Cancer-Initiating Cells

Donald J. Vander Griend, Wouter R. Karthaus, Susan L. Dalrymple et al. · Cancer Research · 2008 · 233 citations · Full text

Embryonic Stem Cell, Lineage Plasticity, Malignant Cancer-initiating Cells +15

Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

Steven Kregel, Kyle J. Kiriluk, Alex M. Rosen et al. · PLoS ONE · 2013 · 176 citations · Full text

Androgen Receptor, Genetics, Normal Prostate +17

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

S. Diane Yamada, Jonathan A. Hickson, Yancey Hrobowski et al. · PubMed · 2002 · 143 citations

Human Ovarian Carcinoma, Endocrine-related Cancer, Metastasis Suppressor Gene +15

Ectopic JAK–STAT activation enables the transition to a stem-like and multilineage state conferring AR-targeted therapy resistance

Su Deng, Choushi Wang, Yunguan Wang et al. · Nature Cancer · 2022 · 138 citations · Full text

Immunotherapy, Tumor Biology, Ectopic Jak–stat Activation +18