John F. Lynas

Novel Inhibitors of the Pseudomonas aeruginosa Virulence Factor LasB: a Potential Therapeutic Approach for the Attenuation of Virulence Mechanisms in Pseudomonal Infection

George R. Cathcart, Derek J. Quinn, Brett Greer et al. · Antimicrobial Agents and Chemotherapy · 2011 · 110 citations · Full text

Pseudomonas Elastase, Pseudomonal Infection, Antimicrobial Chemotherapy +18

Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels

Christopher J. Scott, Andrew McDowell, Lorraine Martin et al. · Biochemical Journal · 2002 · 79 citations · Full text

Wild-type Srta, Antibiotic Adjuvant, Antimicrobial Chemotherapy +19

Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl α-keto aldehydes (glyoxals)

John F. Lynas, Patrick Harriott, Adrienne Healy et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 65 citations

Medicinal Chemistry, Aldo-keto Reductase, Biochemistry +9

Evaluation of Dipeptide α-Keto-β-aldehydes as New Inhibitors of Cathepsin S

Brian Walker, John F. Lynas, Mark A. Meighan et al. · Biochemical and Biophysical Research Communications · 2000 · 37 citations

Biochemistry, Cathepsin S, Medicine +6

Inhibition of escherichia coli glucosamine synthetase by novel electrophilic analogues of glutamine—comparison with 6-diazo-5-oxo-norleucine

Brian Walker, Martin F. Brown, John F. Lynas et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 33 citations

Pharmacology, Biosynthesis, Biochemistry +1