Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: Formulation, characterisation and functionalisation with dornase alfa (DNase)

Jill Deacon, Sharif M. Abdelghany, Derek J. Quinn, +9

Journal of Controlled Release

AntibioticsTobramycin Polymeric NanoparticlesAntibacterial AgentAntimicrobial ChemotherapyMicrobiology +5

Novel Inhibitors of the Pseudomonas aeruginosa Virulence Factor LasB: a Potential Therapeutic Approach for the Attenuation of Virulence Mechanisms in Pseudomonal Infection

George R. Cathcart, Derek J. Quinn, Brett Greer, +4

Antimicrobial Agents and Chemotherapy

Pseudomonas ElastasePseudomonal InfectionAntimicrobial ChemotherapyVirulence MechanismsDrug Resistance +16

Antibody-Mediated Inhibition of Cathepsin S Blocks Colorectal Tumor Invasion and Angiogenesis

Roberta E. Burden, Julie A. Gormley, Thomas J. Jaquin, +8

Clinical Cancer Research

USP17 Regulates Ras Activation and Cell Proliferation by Blocking RCE1 Activity

James F. Burrows, Alyson A. Kelvin, Cheryl McFarlane, +9

Journal of Biological Chemistry

Molecular RegulationImmunologyMolecular BiologyCell ProliferationCytoskeleton +15

A Novel FK506-Like Binding Protein Interacts with the Glucocorticoid Receptor and Regulates Steroid Receptor Signaling

Hayley D. McKeen, Kerry McAlpine, Andrea Valentine, +9

Endocrinology

ImmunologyMolecular BiologyGlucocorticoidGlucocorticoid Receptor90-Glucocorticoid Receptor +18

Impaired Immune Tolerance to<i>Porphyromonas gingivalis</i>Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis

Svetislav Zarić, Charles E. Shelburne, Richard P. Darveau, +4

Infection and Immunity

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationCell Death +24

Rational Design of a (S)-Selective-Transaminase for Asymmetric Synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine

Daniel F. A. R. Dourado, Stefan Pohle, Alexandra T. P. Carvalho, +10

ACS Catalysis

Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles

François Fay, Derek J. Quinn, Brendan Gilmore, +2

Biomaterials

NanoparticlesNano-drug DeliveryGene Delivery

Immunocolloidal Targeting of the Endocytotic Siglec-7 Receptor Using Peripheral Attachment of Siglec-7 Antibodies to Poly(Lactide-co-Glycolide) Nanoparticles

Christopher J. Scott, Waleed M. Marouf, Derek J. Quinn, +4

Pharmaceutical Research

NanotherapeuticsImmunocolloidal TargetingMedicineImmunoengineeringImmunology +6

A secretory leukocyte protease inhibitor variant with improved activity against lung infection

N. D. Camper, Arlene Glasgow, Megan Osbourn, +9

Mucosal Immunology

Protease InhibitorsInflammationCytokineImproved ActivityLung Inflammation +7