Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics

Athanassia Sotiropoulos, Dziugas Gineitis, John W. Copeland, +1

Cell

Signal TransductionSignaling PathwayCell InteractionPhysiologyCellular Regulatory Mechanism +9

Atrophy of S6K1−/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control

Mickaël Ohanna, Andrew K. Sobering, Thomas Lapointe, +7

Nature Cell Biology

Muscle PhysiologyMuscle FunctionMolecular PhysiologyMuscle InjuryCell Division +13

Mutant Actins Demonstrate a Role for Unpolymerized Actin in Control of Transcription by Serum Response Factor

Guido Posern, Athanassia Sotiropoulos, Richard Treisman

Molecular Biology of the Cell

Molecular RegulationMolecular BiologyCytoskeletonSrf ActivationUnpolymerized Actin +17

Deletion of the Carboxyl-Terminal Transactivation Domain of MGF-Stat5 Results in Sustained DNA Binding and a Dominant Negative Phenotype

Richard Moriggl, Valérie Gouilleux‐Gruart, Ruth Jähne, +7

Molecular and Cellular Biology

Amino AcidsMolecular RegulationMolecular BiologySustained Dna BindingTranscriptional Regulation +15

Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers

Matthieu Dos Santos, Stéphanie Backer, Benjamin Saintpierre, +6

Nature Communications

Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal

Rana Abou-Khalil, Fabien Le Grand, Giorgia Pallafacchina, +10

Cell stem cell

Signal TransductionAngiogenesisSignaling PathwaySkeletal MuscleReceptor Tyrosine Kinase +5

S6 Kinase Deletion Suppresses Muscle Growth Adaptations to Nutrient Availability by Activating AMP Kinase

Víctor Aguilar, Samira Alliouachene, Athanassia Sotiropoulos, +15

Cell Metabolism

Muscle PhysiologyMuscle FunctionMolecular PhysiologySignal TransductionSkeletal Muscle +10

Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation

Athanassia Sotiropoulos, Mickaël Ohanna, Cécile Kedzia, +4

Proceedings of the National Academy of Sciences

MechanobiologySkeletal Muscle GrowthSignal TransductionMolecular PhysiologyDevelopmental Biology +12

Evidence for generation of the growth hormone-binding protein through proteolysis of the growth hormone membrane receptor.

Athanassia Sotiropoulos, Laure Goujon, Ghislaine Simonin, +3

Endocrinology

Protein SecretionHuman GrowthImmunologyGrowth Hormone-binding ProteinCell Growth +16

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

Aline Guerci, Charlotte Lahoute, Sophie Hébrard, +10

Cell Metabolism

MechanobiologyMuscle FunctionSignal TransductionMolecular PhysiologyEngineering +8