Henrik Cordes

Network integration and modelling of dynamic drug responses at multi-omics levels

Nathalie Selevsek, Florian Caiment, Ramona Nudischer et al. · Communications Biology · 2020 · 49 citations · Full text

Medicine, Bioinformatics, Molecular Medicine +17

Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling

Marcha Verheijen, Yannick Schrooders, Hans Gmuender et al. · Toxicology Letters · 2018 · 45 citations · Full text

Medicine, Pharmacology, Toxicology +17

A Physiologically Based Pharmacokinetic Model of Isoniazid and Its Application in Individualizing Tuberculosis Chemotherapy

Henrik Cordes, Christoph Thiel, Hélène E. Aschmann et al. · Antimicrobial Agents and Chemotherapy · 2016 · 43 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation

Henrik Cordes, Christoph Thiel, Vanessa Baier et al. · npj Systems Biology and Applications · 2018 · 38 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells

Zoe Weydert, Madhu Lal‐Nag, Lesley Mathews-Greiner et al. · SLAS DISCOVERY · 2019 · 31 citations · Full text

Medicine, Cell Biology, Oncology +17