Concepedia

Author

Henrik Cordes

RWTH Aachen UniversityORCID

Also Known As

H Cordes, Henrik Cordes

20

Publications

347

Citations

11

H-Index

25

Concepts

All Affiliations

RWTH Aachen UniversityEuropean Bioinformatics InstituteMaastricht UniversityKing's College LondonInspire
HC

About

Henrik Cordes is an author at RWTH Aachen University specializing in pharmacokinetic modeling, drug discovery, and pharmacokinetics.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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Pharmacology

2

2

39

3

Drug Discovery

2

2

39

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Health Sciences

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1

17

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Hepatology

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1

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Henrik Cordes

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11

Publications

303

Citations

11

H-Index

YearCitations

Network integration and modelling of dynamic drug responses at multi-omics levels

Nathalie Selevsek, Florian Caiment, Ramona Nudischer,

Communications Biology

2020

49

Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling

Marcha Verheijen, Yannick Schrooders, Hans Gmuender,

Toxicology Letters

2018

43

A Physiologically Based Pharmacokinetic Model of Isoniazid and Its Application in Individualizing Tuberculosis Chemotherapy

Henrik Cordes, Christoph Thiel, Hélène E. Aschmann,

Antimicrobial Agents and Chemotherapy

2016

40

Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation

Henrik Cordes, Christoph Thiel, Vanessa Baier,

npj Systems Biology and Applications

2018

35

A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells

Zoe Weydert, Madhu Lal‐Nag, Lesley Mathews-Greiner,

SLAS DISCOVERY

2019

31

Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients

Christoph Thiel, Henrik Cordes, Isabel Conde,

Archives of Toxicology

2016

23

Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations

Christoph Thiel, Ines Smit, Vanessa Baier,

npj Systems Biology and Applications

2018

22

A Physiology-Based Model of Human Bile Acid Metabolism for Predicting Bile Acid Tissue Levels After Drug Administration in Healthy Subjects and BRIC Type 2 Patients

Vanessa Baier, Henrik Cordes, Christoph Thiel,

Frontiers in Physiology

2019

20

A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations

Christoph Thiel, Henrik Cordes, Lorenzo Fabbri,

PLoS Computational Biology

2017

17

Gene expression databases for physiologically based pharmacokinetic modeling of humans and animal species

Henrik Cordes, Hermann Rapp

CPT Pharmacometrics & Systems Pharmacology

2023

12

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