Kouya Kimoto

A novel solubilization technique for poorly soluble drugs through the integration of nanocrystal and cocrystal technologies

Masatoshi Karashima, Kouya Kimoto, Katsuhiko Yamamoto et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2016 · 69 citations

Nanomedicine, Chemical Engineering, Engineering +8

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2<i>H</i>-benzo[<i>b</i>][1,4]oxazin-6-yl Moiety

Shuhei Ikeda, Hideyuki Sugiyama, Hidekazu Tokuhara et al. · Journal of Medicinal Chemistry · 2021 · 36 citations · Full text

Pharmaceutical Cocrystal Development of TAK-020 with Enhanced Oral Absorption

Kouya Kimoto, Mitsuo Yamamoto, Masatoshi Karashima et al. · Crystals · 2020 · 30 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Tak-020/ga Cc +15

Rational polymorph screening based on slow cooling crystallization of poorly soluble mebendazole

Masatoshi Karashima, Kouya Kimoto, Takashi Kojima et al. · Journal of Crystal Growth · 2013 · 19 citations

Engineering, Polymer Science, Rational Polymorph +7

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore

Y. Tanaka, Masaki Seto, Keiko Kakegawa et al. · Journal of Medicinal Chemistry · 2022 · 13 citations · Full text