Paul N. Valdmanis

Mutations in the <i>FUS/TLS</i> Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

Thomas J. Kwiatkowski, Daryl A. Bosco, Aurélie Leclerc et al. · Science · 2009 · 2.5K citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Somatic Variant +14

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

Edor Kabashi, Paul N. Valdmanis, Patrick A. Dion et al. · Nature Genetics · 2008 · 1.5K citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Mendelian Disorder +10

The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo

Shuo Gu, Lan Jin, Yue Zhang et al. · Cell · 2012 · 287 citations · Full text

Systems Biology, Engineering, Dicer Processing +10

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice

Adi Barzel, Nicole K. Paulk, Yun Shi et al. · Nature · 2014 · 261 citations · Full text

Knockout Mouse, Transcriptional Regulation, Genetics +7

Mutations in the KIAA0196 Gene at the SPG8 Locus Cause Hereditary Spastic Paraplegia

Paul N. Valdmanis, Inge A. Meijer, Annie Reynolds et al. · The American Journal of Human Genetics · 2006 · 191 citations · Full text

Genetic Disorder, Medicine, Genetics +7