Wenbin Hua

Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

Zhiwei Liao, Rongjin Luo, Gaocai Li et al. · Theranostics · 2019 · 422 citations · Full text

Life Sciences, Cell Biology, Molecular Medicine +17

Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

Weifeng Zhang, Gaocai Li, Rongjin Luo et al. · Experimental & Molecular Medicine · 2022 · 323 citations · Full text

Veterinary Medicine, Immunology, Pathology +15

Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

Kangcheng Zhao, Ran An, Qian Xiang et al. · Cell Proliferation · 2020 · 202 citations · Full text

Veterinary Medicine, Cell Biology, Pathobiology +16

Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration

Zhiwei Liao, Shuai Li, Saideng Lu et al. · Biomaterials · 2021 · 138 citations

Life Sciences, Biomedical Sciences, Cell Biology +12

Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress‐Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration

Bingjin Wang, Wencan Ke, Kun Wang et al. · Oxidative Medicine and Cellular Longevity · 2021 · 126 citations · Full text

Life Sciences, Cell Biology, Physiology +17