Killian Oukoloff

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

Killian Oukoloff, Nicolas Coquelle, Manuela Bartolini et al. · European Journal of Medicinal Chemistry · 2019 · 65 citations · Full text

X-ray Crystallography, Protein Assembly, Biochemistry +10

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group

Pierrik Lassalas, Killian Oukoloff, Vishruti Makani et al. · ACS Medicinal Chemistry Letters · 2017 · 54 citations · Full text

Medicinal Chemistry, Enantioselective Synthesis, Bioorganic Chemistry +13

Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases

Anne‐Sophie Cornec, Ludovica Monti, Jane Kovalevich et al. · Journal of Medicinal Chemistry · 2017 · 48 citations · Full text

Drug Target, 5-Lox-derived Eicosanoids, Neurochemical Biomarkers +28

A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model

Bin Zhang, Yuemang Yao, Anne‐Sophie Cornec et al. · Molecular Neurodegeneration · 2018 · 41 citations · Full text

Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies

Killian Oukoloff, Goodwell Nzou, Carmine Varricchio et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text