Anne‐Sophie Cornec

Brain-Penetrant, Orally Bioavailable Microtubule-Stabilizing Small Molecules Are Potential Candidate Therapeutics for Alzheimer’s Disease and Related Tauopathies

Kevin Lou, Yuemang Yao, Adam T. Hoye et al. · Journal of Medicinal Chemistry · 2014 · 91 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer’s Disease and Related Tauopathies

Jane Kovalevich, Anne‐Sophie Cornec, Michael J. James et al. · Journal of Pharmacology and Experimental Therapeutics · 2016 · 67 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases

Anne‐Sophie Cornec, Ludovica Monti, Jane Kovalevich et al. · Journal of Medicinal Chemistry · 2017 · 50 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model

Bin Zhang, Yuemang Yao, Anne‐Sophie Cornec et al. · Molecular Neurodegeneration · 2018 · 43 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

One “Click” to Access Push–Triazole–Pull Fluorophores Incorporating a Pyrimidine Moiety: Structure–Photophysical Properties Relationships

Anne‐Sophie Cornec, Christine Baudequin, Catherine Fiol‐Petit et al. · European Journal of Organic Chemistry · 2013 · 35 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14