John Pyles

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

Carole R. Baskin, Helle Bielefeldt‐Ohmann, Terrence M. Tumpey et al. · Proceedings of the National Academy of Sciences · 2009 · 365 citations · Full text

Higher Level of Replication Efficiency of 2009 (H1N1) Pandemic Influenza Virus than Those of Seasonal and Avian Strains: Kinetics from Epithelial Cell Culture and Computational Modeling

Hugh Mitchell, Drew Levin, Stephanie Forrest et al. · Journal of Virology · 2010 · 79 citations · Full text

Replication Efficiency, Viral Replication, Viral Evolution +11

A Chimeric Multi-Human Epidermal Growth Factor Receptor-2 B Cell Epitope Peptide Vaccine Mediates Superior Antitumor Responses

Naveen Dakappagari, John Pyles, Robin Parihar et al. · The Journal of Immunology · 2003 · 75 citations

Vaccination, Tumor Immunology, Vaccine Target +14

Delta inulin polysaccharide adjuvant enhances the ability of split-virion H5N1 vaccine to protect against lethal challenge in ferrets

Robert C. Layton, Nikolai Petrovsky, Andrew P. Gigliotti et al. · Vaccine · 2011 · 66 citations

Vaccination, Veterinary Vaccine, Cross-protection +12

Neurovirulence of H5N1 Infection in Ferrets Is Mediated by Multifocal Replication in Distinct Permissive Neuronal Cell Regions

Jennifer R. Plourde, John Pyles, Robert C. Layton et al. · PLoS ONE · 2012 · 48 citations · Full text

Viral Pathogenesis, Pathology, Multifocal Replication +22