Anna Bruchez

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

Marceline Côté, John Misasi, Tao Ren et al. · Nature · 2011 · 680 citations · Full text

Small Molecule Inhibitors, Niemann–pick C1, Medicine +9

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

Anna Bruchez, Ky Sha, Joshua C. Johnson et al. · Science · 2020 · 121 citations · Full text

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

Sarah Roelle, Nidhi Shukla, Anh Pham et al. · PLoS Biology · 2022 · 47 citations · Full text

Virus Structure, Viral Evolution, Emerging Infectious Diseases +13

Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

Nidhi Shukla, Sarah Roelle, Vinicius G. Suzart et al. · PLoS Pathogens · 2021 · 34 citations · Full text

Sars-cov-2 Spike, Spike Proteins, Pathogenesis +11

Inhibition of Ebola Virus Infection: Identification of Niemann-Pick C1 as the Target by Optimization of a Chemical Probe

Kyung‐Ae Lee, Tao Ren, Marceline Côté et al. · ACS Medicinal Chemistry Letters · 2012 · 31 citations · Full text