Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

Marceline Côté, John Misasi, Tao Ren, +8

Nature

Small Molecule InhibitorsNiemann–pick C1MedicineAntiviral Drug DevelopmentAntiviral Therapy +7

Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike

Jérémie Prévost, Romain Gasser, Guillaume Beaudoin-Bussières, +32

Cell Reports Medicine

Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission

Bradley Pickering, Oliver Lung, Finlay Maguire, +37

Nature Microbiology

Viral EvolutionBroad-host-range VirusesEvolutionary BiologyImmunologySustained Evolution +10

Delivery of MicroRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux <i>in Vitro</i> and <i>in Vivo</i>

My-Anh Nguyen, Hailey Wyatt, Leah C. Susser, +10

ACS Nano

NanoparticlesNanomedicineNanoparticle CharacterizationEngineeringCardiovascular Disease +12

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

Wenwei Li, Yaozong Chen, Jérémie Prévost, +27

Cell Reports

Filoviruses Require Endosomal Cysteine Proteases for Entry but Exhibit Distinct Protease Preferences

John Misasi, Kartik Chandran, Jinyi Yang, +7

Journal of Virology

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses

Alexandra Tauzin, Shang Yu Gong, Guillaume Beaudoin-Bussières, +34

Cell Host & Microbe

VaccinationVaccine DevelopmentSars-cov-2 SpikeHumoral ResponseImmunology +7

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity

Shang Yu Gong, Debashree Chatterjee, Jonathan Richard, +11

Virology

Viral EvolutionSingle MutationsVaccine TargetViral PathogenesisImmunology +6

Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission

Bradley Pickering, Oliver Lung, Finlay Maguire, +36

BiologyViral EvolutionDivergent LineageEmerging Infectious DiseasesNatural Sciences +11

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses

Debashree Chatterjee, Alexandra Tauzin, Lorie Marchitto, +29

Cell Reports

VaccinationVaccine DevelopmentVaccine TargetImmunologyContinuous Emergence +9