Visualizing structure and transitions in high-dimensional biological data

Kevin R. Moon, David van Dijk, Zheng Wang, +10

Nature Biotechnology

High-dimensional Biological DataEngineeringComputational BiologyData VisualizationComputational Visualization +4

Quantifying the effect of experimental perturbations at single-cell resolution

Daniel B. Burkhardt, Jay S. Stanley, Alexander Tong, +7

Nature Biotechnology

MicroscopyMedicineExperimental PerturbationsSingle-cell BiologyCell Biophysics +5

Using long-read sequencing to detect imprinted DNA methylation

Scott Gigante, Quentin Gouil, Alexis Lucattini, +8

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyMolecular Genetics +20

Multiscale PHATE identifies multimodal signatures of COVID-19

Manik Kuchroo, Jessie Huang, Patrick Wong, +18

Nature Biotechnology

Multiscale Phate IdentifiesViral DiagnosticsCovid-19 PandemicMolecular BiologyVirology +4

Single-cell analysis reveals inflammatory interactions driving macular degeneration

Manik Kuchroo, Marcello DiStasio, Eric Song, +22

Nature Communications

Quantifying the effect of experimental perturbations at single-cell resolution

Daniel B. Burkhardt, Jay S. Stanley, Alexander Tong, +7

EngineeringMicroscopyTranscriptomics TechnologyGraph Signal ProcessingCell Biophysics +21

An environmentally responsive transcriptional state modulates cell identities during root development

Marina Oliva, Tim Stuart, Dave Tang, +8

Root DevelopmentGeneticsMost Lineage TrajectoriesPlant DevelopmentTranscriptional Regulation +17

Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations

Jingjing Ren, Rihao Qu, Nur-Taz Rahman, +16

Blood Advances

Defining and benchmarking open problems in single-cell analysis

Malte D. Luecken, Scott Gigante, Daniel B. Burkhardt, +47

Using long-read sequencing to detect imprinted DNA methylation

Scott Gigante, Quentin Gouil, Alexis Lucattini, +8