<i>ACVR1</i> ^<i>R206H</i> receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A

Sarah Hatsell, Vincent Idone, Dana M. Alessi Wolken, +17

Science Translational Medicine

Activin FamilySclerostinCell DeathOsteogenesisOsteoporosis +17

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

Vincent Idone, Christina Tam, John A. Goss, +3

The Journal of Cell Biology

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

Christina Tam, Vincent Idone, Cecilia Devlin, +6

The Journal of Cell Biology

A Process for Controlling Intracellular Bacterial Infections Induced by Membrane Injury

Deepannita Roy, David R. Liston, Vincent Idone, +6

Science

Protein SecretionMicrobial PathogensImmunologyCytoskeletonBacterial Pathogens +21

Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop

Senem Aykul, Richard A. Corpina, Erich J. Goebel, +17

eLife

Molecular BiologyCytoskeletonActivin ACellular PhysiologySignaling Pathway +15

Effect of an Orphan Response Regulator on <i>Streptococcus mutans</i> Sucrose-Dependent Adherence and Cariogenesis

Vincent Idone, Stacy Brendtro, R. Dean Gillespie, +8

Infection and Immunity

Microbial PathogensStreptococcus MutansBacteriologyGlycobiologyMicrobial Physiology +20

The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent

Jaymin Upadhyay, Liqin Xie, Lily Huang, +18

Journal of Bone and Mineral Research

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity

Erich J. Goebel, Richard A. Corpina, Cynthia S. Hinck, +12

Proceedings of the National Academy of Sciences

Structural CharacterizationMolecular BiologyReceptor SpecificityTgfβ Family LigandsCell Signaling +17

Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

Senem Aykul, Lily Huang, Lili Wang, +18

Journal of Clinical Investigation

SclerostinImmunologyPathologyCytoskeletonOrthopaedic Surgery +20

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

Parsa Akbari, Olukayode Sosina, Jonas Bovijn, +58

Nature Communications